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Listen to this oral presentation on ‘Battling Bad Science’ by Ben Goldacre http://www.ted.com/talks/ben_goldacre_battling_bad_science?language=en and think the following questions: 

  • What does he say is the weakest form of evidence?
  • Why is a control group important when conducting an experiment or trial?
  • What example of publication bias does he give?
  • What does he say is the biggest single ethical problem in medicine today?


To be able to critically appraise well, you need to be able to: 

  • Make sense of research evidence
  • Understand the methods and the results of the research evidence
  • Assess the reliability and validity of it
  • Assess if the relevance and quality of it is good enough for decision making and implementation into practice


Then read the following paper and decide which CASP checklist is appropriate to use


Lean, M.E., Leslie, W.S., Barnes, A.C., Brosnahan, N., Thom, G., McCombie, L., Peters, C., Zhyzhneuskaya, S., Al-Mrabeh, A., Hollingsworth, K.G. and Rodrigues, A.M., 2017. Primary care-led weight management for remission of type 2 diabetes (DiRECT): an open-label, cluster-randomised trial. The Lancet.

Critically appraise this paper using the CASP checklist and write a paragraph (300-400 words) on your critique of the paper based on your CASP observations.  


Tags: Research, Statistics, CASP Checklist